Drugs

Liver disease is a common cause of premature death in the UK. Recently, The Lancet Commission on Liver Disease highlighted the financial impact liver disease places on the national healthcare system and businesses, and suggested strategies to reduce these burdens. The negative impacts of liver disease on citizens under the age of 65 in the
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Acute kidney injury is a common condition seen by clinicians in different settings. An article published in the Clinical Kidney Journal this 2017 provided an overview of the current diagnosis and clinical management of this condition. An article published in the Clinical Kidney Journal this 2017 provided an overview of the current diagnostic methods and
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Community acquired pneumonia (CAP) is a common cause of morbidity and mortality worldwide. Recent advances in research and technology have helped in the understanding of the disease which in turn aids treatment and management. Community acquired pneumonia is one of the main causes of hospital admissions and healthcare professionals encounter community acquired pneumonia in different
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Respiratory Syncytial Virus (RSV) is the most common virus causing acute lower respiratory infection in young children. A recent comprehensive review study gives an updated estimate of the worldwide impact of RSV and provides key information to direct future vaccine development and implementation policy. Acute lower respiratory tract infection (ALRI), usually pneumonia or bronchiolitis, is
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  Hyperhidrosis is a common medical condition characterized by excessive sweating. A recent systematic literature review investigated the efficacy and safety of several common Hyperhidrosis therapies.   Hyperhidrosis is a chronic autonomic disorder characterized by excessive sweating that affects approximately 4.8% of the United States population. The condition can significantly reduce the quality of life
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Bordetella pertussis is a gram-negative bacillus which causes mild respiratory symptoms in adults but can be a life-threatening infection in children. In 2017, a group of researchers led by Mark Ebell, M.D. did a systematic review on the clinical diagnosis of this infection. Bordetella pertussis is a gram-negative bacillus which causes a mild respiratory infection
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There is an increased interest from policy makers into the emergency admissions andhospitalisation of individuals in nursing homes. A study was conducted to examine thehospitalization rate of nursing homes after the implementation of the INTERACT program. The Interventions to Reduce Acute Care Transfers, INTERACT program, aims to increase the availability and quality of care at
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  Researchers have systematically evaluated antibiotic use in patients and concluded that antibiotics are still being overused.   Adverse drug effects are any injuries or negative reactions caused by taking a medication and are common even in everyday medications such as antibiotics. Recent recommendations have advised fewer antibiotic prescriptions, however, research has shown that as
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Viral infection with the hepatitis A has a low prevalence in Europe; however, a retrospective analysis found that while overall hepatitis A prevalence is decreasing, some regions still have a moderate to high risk of hepatitis A infection.   Hepatitis A is a disease caused by viral infection of the liver by the hepatitis A
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Rheumatoid arthritis affects 1% of the population and can cause permanent joint destruction and death. Chronic inflammation associated with rheumatoid arthritis is known to play a role in predisposing patients to heart disease and heart failure.   Mortality caused by rheumatoid arthritis is predominantly due to cardiovascular complications. With 50% of cardiovascular disease associated deaths
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Metabolic syndrome is a group of risk factors that increase the likelihood of developing heart disease and diabetes. Previous studies have identified aerobic and resistance exercise as protective factors that potentially reduce the risk of metabolic syndrome. A study on middle-aged healthy adults found that both aerobic and resistance exercises decrease the risk of developing
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  Chikungunya virus is a mosquito-borne virus for which recent outbreaks in human populations have drawn a lot of interest from the scientific community. Luckily, a group of investigators recently reported the development of a monoclonal antibody with therapeutic potential in a macaque monkey model of the disease. Chikungunya virus (CHIKV) can be transmitted to
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A study recently published in the American Journal of Clinical Nutrition sought to determine the most effective way to increase hemoglobin levels in anemic women, comparing iron supplementation with the use of iron ingots. Researchers concluded that the hemoglobin concentration did not significantly differ between the control group and either the iron ingot or iron-supplement group.
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There has been a growing interest in the different applications of nanomaterials in the field of medicine. An article published in Nanomedicine: Nanotechnology, Biology, and Medicine showed the ways in which Laponite®, a synthetic clay made of nanomaterials, can be of use in clinical practice.   Current advances in technology have provided many opportunities to
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A recent clinical trial investigated the use of Levosimendan (a drug used for the management of congestive heart failure) for reducing mortality rates amongst patients with perioperative heart dysfunction, a major complication associated with heart surgery. Previous small trials have suggested this therapeutic may result in a high rate of survival for patients undergoing heart
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Urinary tract infection (UTI) related to urinary catheter use can cause many problems in nursing home residents. A USA nationwide project to improve care in this area successfully reduced the number of catheter-associated UTIs.   A urinary catheter is a small flexible tube inserted via the urethra into the bladder to drain urine. It is
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Antibiotic use for respiratory tract infections is the mainstay therapy in primary care but a recent study shows that hospital reconsultations with symptoms of lower respiratory tract infections (LRTI) can be significantly reduced with delayed antibiotic prescription.   Infections of the respiratory tract are a regular reason for primary care consultations and patients often present
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Doctors sometimes prescribe multiple medications to patients in an attempt to increase the effectiveness of treatment. This study calls into question the use of combination therapy for schizophrenia, showing that they are no more effective than one medication alone.   Schizophrenia is a serious mental illness that affects countless men and women each year. Antipsychotic drugs,
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Ulcerative colitis is an inflammatory bowel disease for which new therapeutic strategies are greatly needed. A recent phase III clinical trial investigating the impact of a Janus Kinase (JAK) inhibitor tofacitinib, in the treatment of ulcerative colitis, provides a convincing proof of concept supporting the efficacy of this compound for induction and maintenance therapy.  
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Polyneuropathy is a painful condition, severe enough that, it often leads physicians to make the decision to initiate opioid therapy for pain relief. Gaining insight into the effects of long-term opioid use in patients with polyneuropathy may provide physicians with valuable information that could drive positive change in the management of the condition.   Polyneuropathy
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Medication overuse headache (MOH) is defined as the worsening of pre-existing headache with overuse of headache medication, and treatment has consisted of abrupt drug withdrawal accompanied by severely unpleasant symptoms. Safe analgesics like steroids and acetaminophen were found to provide no significant benefit compared to placebo when treating withdrawal headache in patients with MOH.  
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The World Health Organization estimates that 3.3 million deaths worldwide are caused by alcohol use. Drinking alcohol can also lead to serious health complications such as liver disease and cancer. The most severe form of alcohol use is referred to as alcohol dependence (AD) and is considered to be a chronic disease.   At present,
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