Drugs

Researchers in Japan have evaluated a new multimodal approach for neck rejuvenation. Cosmetic neck rejuvenation is one of the most challenging cosmetic procedures for clinicians. A multi-modal approach is necessary because so many factors contribute to the aging of the neck. A multimodal approach to rejuvenate the neck was reported and published in the Journal
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A recent meta-analysis of randomised controlled trials assessed the efficacy of two drug treatments in reducing mortality in heart failure patients. Chronic heart failure affects 1-2% of the adult population in developed countries and it has one of the highest morbidity and mortality rates for cardiovascular disease globally. It is thus crucial to decrease the
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In a recently published review, researchers examine the relationship between antihypertensive medications and the risk of major cardiovascular events. How is Blood Pressure Measured? When the heart beats, it pushes blood through your arteries to the rest of your body.  This creates pressure in the blood vessels.  The amount of pressure in the arteries is
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Investigators review rituximab for the treatment of various autoimmune rheumatic diseases to determine how useful it is for approved and off-label use. Improved understanding of autoimmune rheumatic diseases, such as rheumatoid arthritis, has helped advance the types of therapeutic options available. For example, biologic therapies are very promising and can greatly improve patients’ quality of
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Dienogest has been extensively investigated as a treatment for endometriosis. A new study evaluates its efficacy in treating symptomatic adenomyosis. What is Adenomyosis? Adenomyosis is a condition that involves the encroachment, or movement, of endometrial tissue lining the uterus. Adenomyosis differs from endometriosis in that the endometrial tissue “pushes” into the muscles of the uterus
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Researchers investigated whether extremely high levels of HDL cholesterol are associated with increased mortality in men and women. HDL cholesterol, often known as “good” cholesterol, is known to have an inverse relationship with cardiovascular disease and mortality—higher HDL cholesterol levels are associated with lower cardiovascular disease. Randomized clinical trials, however, have failed to prove that
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A recent study sheds new light on the genetic basis of alcohol dependence and major depression, which could help develop new treatments for these conditions. Although the comorbidity of alcohol dependence and major depression is recognized, the underlying basis of their co-occurrence is not well understood. Studies indicate that alcohol dependence increases the risk of
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A recent study investigated whether there is a link between consuming high glycemic foods and the accumulation of amyloid-β plaques in older adults. More than one in eight Americans aged over 65 years is affected by Alzheimer’s disease, the most common form of dementia. The hallmark characteristic of Alzheimer’s disease is the formation and accumulation
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The International Bioinformatics Workshop that recently took place in China presents an opportunity to learn about new findings and techniques in the field. Bioinformatics is an increasingly important scientific field combining computer science, math, statistics, and engineering to analyze the vast quantities of biological data that researchers are generating. In Genome Biology, Zheng and Zhong
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A new study examines the potential association between dietary consumption of pesticides and pregnancy outcomes of women undergoing fertility treatment. Fruits and vegetables are a necessary component of a balanced diet. However, the number one source of pesticides is from those same fruits and vegetables. There are guidelines in place to manage pesticide levels and
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Researchers examined previous studies on chronic kidney disease and contributing factors, exploring how they might affect bone loss and heart disease. In addition to reducing the body’s ability to remove waste, controlling fluid levels, and managing blood pressure, chronic kidney disease (CKD) also impacts a number of processes related to aging and cardiovascular disease. Exploring
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A recent study reviews the occurrence, diagnosis, and treatment of early-onset inflammatory bowel disease with respect to its causes and epidemiology. Early-onset inflammatory bowel disease (IBD) is classified as a diagnosis of ulcerative colitis, Crohn’s disease or inflammatory bowel disease in children under the age of 10 and occurs in a chronic state.  Early-onset inflammatory
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A large-scale multinational study investigates the effect of evolocumab on regulating LDL cholesterol levels and managing the risk of heart disease. Low-density lipoprotein (LDL) cholesterol is a well-researched marker for cardiovascular disease, with lower LDL levels being associated with lower risk of cardiovascular disease. Proprotein convertase subtilisin-kexin type 9 (PCSK9) is an enzyme that plays
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A new study investigates the effectiveness of measuring procalcitonin levels to gauge the efficacy of antibiotics in treating acute respiratory infections. Procalcitonin is the precursor of the peptide hormone calcitonin. Calcitonin is produced as procalcitonin primarily by the thyroid gland and reduces the levels of calcium in the blood by inhibiting the activity of osteoclasts,
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Researchers have outlined a clinical trial protocol to evaluate acupuncture points in acupuncture therapy and evaluate their effectiveness in combating chemotherapy nausea. Vomiting and nausea are very well-known side effects of chemotherapy. Managing these side effects is challenging because antiemetic drugs have unpleasant side effects. Research has shown that acupuncture has been effective in reducing
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Iron deficiency anaemia is common condition among women. Researchers from Switzerland determine which supplement dosing schedule is most effective for iron absorption. Iron deficiency anaemia (IDA) is a common condition among women due to their menstrual period. Because of this, iron tablets are often prescribed to be taken daily in order to maintain normal iron
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Healthcare professionals have acknowledged that children are at risk of radiation overexposure during CT scans and are developing strategies to minimize this risk. Bumps and bruises are common childhood injuries from which children quickly recover. Unfortunately, some childhood injuries are much more serious and require hospitalization. An article recently published on the American website DOTmed
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Malaria is a deadly disease spread by mosquitoes. New research, published in Science, attempts to halt the spread of the malaria parasite before it can get to humans. Malaria is a deadly disease that affects millions of people annually. The malaria parasite, Plasmodium falciparum, is transmitted by the Anopheles mosquito, which carries the parasite in
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In 2017, three different pharmaceutical companies have found that a protein responsible for cancer-induced anorexia may benefit people suffering from obesity. Currently, there are many people suffering from obesity worldwide. However, attempts to lose weight are unsuccessful for some people despite engaging in diets and strenuous physical activities. A recent news article published in Science
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