Clinical Trials & Research

Implementing clinical breast examinations may help with breast cancer diagnosis at an early stage or provide awareness of breast health in low to middle income countries.   The lack of symptoms associated with breast cancer make screenings essential. Though mammograms are used to detect abnormalities in the breast, but they are impractical or unavailable in
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Polymeric micelles are an important class of targeted drug delivery systems that act as carriers of chemotherapeutic agents. A recent review summarized the research being carried out in the development and use of polymeric micelles and micelle-forming drug-polymer conjugates for cancer therapy.   A common problem in cancer treatment is the untargeted delivery of highly
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Researchers from Duke University in North Carolina produced pathogen-resistant crops without compromising the plant’s yield and fitness.   Plants are commonly attacked by microbial, viral or fungal pathogens. Improving crop production involves the applications of pesticides. In recent years, genetically modified pathogen-resistant crops that express a high level of immune proteins have been produced. One
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Hospital acquired infections are rampant today. Understanding their origin and how they spread is key to avoiding infection. A recent study characterized bacteria found on hospital surfaces, patients and staff in a new hospital over a 1 year period.   An individual’s immune system protects them from foreign bodies and organisms. For an immune system
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The 6 MAIN Causes of Tooth Discoloration RED WINE: Red wine is notorious for staining teeth. The acids in wine eat away at tooth enamel, creating rough spots that make teeth more vulnerable to staining. And it also contains chromogens and tannins, which help the color stick to your teeth.   TEA/COFFEE: Like wine, tea and coffee are rich
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Recently published guidelines outline how physicians should deprescribe or taper patient use of proton pump inhibitors, a commonly prescribed class of drugs with problematic long term use.   Proton–pump inhibitors (PPI’s) are a class of drugs recommended for people who suffer from increased acidity in their stomach. The acidity could be the result of a
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Current treatment of osteoarthritis involves nonsteroidal anti-inflammatory drugs (NSAIDs) which are accompanied by numerous adverse effects. Chondroitin sulfate represents a viable alternative that is equally as effective in pain relief and function restoration.   Osteoarthritis (OA) is a disease in which the cartilage providing cushioning between joints wears down. This can result in pain, stiffness,
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The internet is a storehouse of information and, in recent years, patients have taken to searching the internet to decipher symptoms, diseases and possible treatments for illnesses; a phenomenon commonly referred to as “Dr. Google”. Flemish researchers investigated the link between Dr. Google and doctor-patient interactions and found that internet searches did not negatively affect
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Delirium is a costly yet preventable, common post-surgical complication in the elderly population. A recent study shows that an intervention program called mHELP greatly reduces cases of delirium post-surgery in older patients.   Delirium, an acutely disturbed state of mind, is considered the most common complication following surgery in the elderly population. Delirium can have
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In a 2017 study, researchers sought to determine the role of the peroxisome proliferator-activated receptor delta (PPAR-delta) cell signaling pathway in exercise-induced improvements in endurance. The researchers found PPAR-delta improves endurance by reducing glucose release and metabolism and increasing fat metabolism in muscle tissue.   Exercise is believed to improve endurance by reducing the extent
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New opioid drugs with reduced side effects are in development.   Chronic pain is a serious and growing concern. It impacts 1/3 of Americans and severely degrades quality of life. To date, the best treatment to manage chronic pain are opioids such as morphine and fentanyl. Unfortunately, opioids have many side effects, including dependence, addiction,
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Current research shows that rapid detection of Adrenoleukodystrophy can significantly reduce the rate of potential neurological damage in the life span of a male child who is genetically prone to acquiring the disease.   Adrenoleukodystrophy (ALD) is an X-linked genetic disorder that affects the adrenal gland and the nervous system in boys. In its most
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A new article describes research performed on different methods of minimizing pain associated with injectable facial noninvasive cosmetic treatments.   Botulinum toxin, commonly known as Botox (BTX), and soft-tissue filler (STF) have become the two most frequently performed nonsurgical cosmetic facial treatments in the United States, with roughly between 2.1 million and 4.3 million procedures,
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A phenomenon known as antibody-dependent enhancement, whereby previous infection by a different serotype of the same virus increases their infectivity, can seriously increase the vulnerability of individuals to some viral infections. In a recent study published in Science, a group demonstrated that this phenomenon may seriously impact individuals at risk of contracting the Zika virus
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A recently published article compiles an overview of psoriasis diagnosis and treatment for this increasingly prevalent autoimmune inflammatory disease.   Psoriasis is a multisystem inflammatory disease which presents primarily at the skin and joints. It has been estimated to impact 1.7% of Canada’s population. Affecting all sexes equally, the condition is likely to occur between
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There is a new hybrid-molecule against disease-causing, drug resistant bacteria engineered by the researchers at the Rockefeller University.   Unfortunately, the human immune system is poorly equipped to destroy certain disease-causing, drug-resistant bacteria. The problem is that some antibodies do not recognize carbohydrates on bacterial cell walls, meaning the antibodies will not bind to the
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In case you missed it, here are the biggest headlines of the week! Effects of Mediterranean Diet on Endothelial Function and Blood Pressure A group of researchers conducted a randomized control trial to determine whether adherence to Mediterranean diet improved endothelial function and lowered blood pressure levels … [read more]   Is Ketamine with Electroconvulsive
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Multiple sclerosis is a neurologic disease that causes fatigue, loss of sensation, vision impairment, and difficulty with muscle control and coordination. Using a mouse model, researchers found evidence that treatment with nimodipine slowed the rate of nerve cell demyelination and also fostered remyelination.   Multiple sclerosis (MS) is an autoimmune disease which causes damage to
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