Cancer

A new study reveals the importance of examining thrombocytosis in primary care for cancer diagnoses.   Cancer is one of the leading cause of death in developed countries. It is critical for primary caregivers to recognize the possibility of cancer and give access to specialists for further diagnosis. Thrombocytosis, an elevated platelet count, is an emerging
0 Comments
Recent observational studies suggest that administrating aspirin to patients at high-risk of developing cardiovascular diseases may also reduce colorectal cancer incidence and mortality. A new meta-analysis aimed to compare the efficacy of aspirin with established colorectal cancer screening strategies confirmed that aspirin may be equally effective.   A low daily dose of aspirin is routine
0 Comments
Lung cancer screening programs have been documented to reduce the mortality associated with lung cancer among high-risk patients, but the feasibility of their implementation in a clinical setting has been questioned. A recent investigation tested a small-scale implementation of such program and the results suggest that although it may indeed be effective, the costs and
0 Comments
A population-based study aimed to estimate survival inequalities for several subtypes of leukemia was performed. It was found that inequalities between countries have narrowed somewhat, however there remains much room for improvement.   Leukemia, a term used for a group of cancers of the blood, begins in the bone marrow and creates many malformed white
0 Comments
Colorectal cancers are benign epithelial tumors that often acquire malignancy and hence, they are surgically removed following detection and intensive colonoscopic surveillance is advised afterwards. A recent retrospective trial focusing on intermediate-risk patients suggests that a subgroup of lower-risk patients may not require extensive surveillance and that only the first couple of surveillance examinations impart benefits.
0 Comments
Although prostate cancer is remarkably frequent among men, the availability of non-invasive early detection methods, such as PSA blood levels tests and digital rectal examination, greatly facilitates its detection and subsequent treatment. However, a recent update of a clinical trial performed over 19 years suggests that implementing a systematic prostate cancer screening program using these
0 Comments
Genetic tests for breast cancer prevention and treatment are now implemented in most modern medical facilities. A recent review highlights the role of genetic testing in this context and describes when, why and how it should be performed.   Breast cancer ranks among the top most frequent cancers in the U.S. affecting one out of
0 Comments
A prospective cohort study, published in the British Medical Journal, reports that active commuting, particularly cycling, can significantly reduce the risk of all-cause mortality, cardiovascular disease, and cancers.   Modern societies are plagued with sedentary lifestyles, unhealthy eating habits, and physical inactivity, which collectively contribute to higher risk of disease and decrease the quality of
0 Comments
In laboratory studies on heart cells and mice, researchers showed that the drugs dexamethasone and rapamycin raise glucose levels and increase the toxicity of the cancer drug doxorubicin. Further investigations suggest there is a cellular pathway dependent on glucose that sensitizes normal cells to doxorubicin. This increased toxicity can be reversed by reducing the glucose
0 Comments
` Individuals with localized prostate cancer have 3 treatment options which include; EBRT (radiation), radical prostatectomy (surgery) and active observation. Each modality has its positives but this study focuses on the negatives associated with each.   In a new prospective study, 2,550 men were grouped based on their treatment modality. 1,523 (59.7%) men underwent radical
0 Comments
Increases in colorectal adenoma (the initial sage of colorectal cancer) are reported to be associated with long-term use of antibiotics. A study carried out to assess long-term and short-term use of antibiotics in relation to colorectal adenomas found that long-term antibiotic use in early/middle adulthood is associated with increased risk of colorectal adenoma.   In
0 Comments
A recent study published in PNAS identifies the protein Neil1, involved in DNA damage repair, as protective against aflatoxin-induced liver cancer. Mice lacking Neil1 had an increased risk of developing aflatoxin-induced hepatoceullar carcinoma.   HCC is most common in developing countries and accounts for an estimated 700,000 death per year. This high mortality rate highlights
0 Comments