Cancer

A recent study tests a multi-gene classifier, an ultralow-risk threshold, to determine if it can identify indolent tumours and breast cancer risk. Breast cancer is a life-threatening medical condition resulting in a wide range of outcomes. Recurrence of a tumour following initial diagnosis can range from a few months to several years. Molecular profiling is
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Nivolumab is an immune checkpoint inhibitor used in the treatment of melanoma. In an article published in JAMA Oncology, a group of researchers analyzed data from phase 3 clinical trials assessing the effects of nivolumab on patients with advanced melanoma treated beyond disease progression.   Nivolumab is a human monoclonal antibody which functions as an
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Mammography screening is touted as the best tool to detect early-stage breast cancer. A recent study looked at American women’s awareness of the benefits and risks associated with mammograms and whether these would influence their decision to undergo mammography. Breast cancer is a leading cause of cancer death in women worldwide. Early-stage breast cancer can
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Population-disease metrics are crucial in guiding the distribution of resources to health interventions and in implementing public health initiatives but are not always available for all diseases. Google, a popular search engine, could be a viable source of population-disease metrics when other sources are lacking. This study analyses the ability of Google to predict cancer
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A recent meeting of 21 scientists updated guidelines on several chemicals and their potential in causing urinary tract cancer.  The most current evidence is awaiting publication, recommending that 7 different substances be categorized as “possibly carcinogenic to humans”. Cancer arises when cells in our bodies undergo genetic damage or a disruption of normal cellular process
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A recently published report shows that high intake of the dietary omega-6 polyunsaturated fatty acid (PUFA) arachidonic acid could increase your risk for colorectal adenoma (precancerous polyps that can develop into cancer).   Colorectal cancer is the second most common type of cancer, accounting for 13% of all cancers.1 With improved endoscopic screening for adenomas, the
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Researchers find that proactively removing more than 24 lymph nodes can help the long term outcome of patients with Oral Cavity Squamous Cell Carcinoma. Surgical nodal dissection or excision involves removing lymph nodes affected by cancer and simultaneously determining the stage of cancer.Benefits of such measures include staging cancer and limiting the spread of cancer
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Human PapillomaVirus (HPV) diagnostic tests are commonly performed among PAP positive women, but their impact on the detection, severity and disease management of cervical intraepithalialneoplasia (CIN) remains poorly understood. A recent study suggests HPV tests may indeed improve timing and detection rates of Atypical Squamous Cells and CIN among PAP positive women.   Human PapillomaVirus
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 A recent study used nutritional metabolomics to identify diet-related metabolites as potential breast cancer risk factors. The findings show that prediagnostic serum concentrations of metabolites related to alcohol, vitamin E, and animal fats were associated with an increased breast cancer risk. Breast cancer is currently the leading global cause of cancer-related deaths in women. There
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A small-molecule drug inhibitor called vismodegib successfully treated a dire case of infiltrative basal cell carcinoma. According to the authors, this case qualifies as a first to report a complete remission for this subset of skin cancer.   Basal cell carcinoma (BCC) is one of the most common types of skin cancer. For patients with
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  Human papillomavirus (HPV) is responsible for causing cervical cancer in many women worldwide, and successful screening programs have been accredited with helping to increase the capacity to identify and treat precancerous and pre-invasive disease. Quantitative methylation of the POU4F3 gene biomarker is a valuable tool for high-grade CIN detection.   Cervical cancer, caused by the human
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Cancer encompasses a range of diseases with varying mortality rates. A recent study has shown how cancer mortality rates have changed and influenced life expectancy over 30 years and have uncovered discrepancies in cancer control efforts between different populations.   Cancer is predicted to become the primary cause of global morbidity and mortality, surpassing cardiovascular
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A recent study in JAMA Oncology compared the effectiveness of mammography alone vs. mammography in combination with MRI or ultrasonography in breast cancer screening. The results showed that combinatorial approaches could have a significant impact on detection rates and sensitivity for patients undergoing screening for recurrence.   Breast cancer screening is an indispensable practice in
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 The Dietary Inflammatory Index indicates the inflammatory or immune response to various foods. Authors of a recent study investigated if eating food with lower Dietary Inflammatory Indices decreases the chances of fatal breast cancer.   Breast cancer is the most common cancer in women worldwide, and the main cause of cancer-related death. As such, breast
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Long-term androgen deprivation therapy (ADT) in combination with abiraterone, a selective inhibitor of CYP17, an enzyme needed for androgen production, is associated with significantly higher rates of overall and failure-free survival than ADT alone among men with locally advanced or metastatic prostate cancer. Cancer of the prostate is the most prevalent disease in men, with
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A Chinese study suggests cancer risk is directly associated with the dietary inflammation index of the food one consumes. Foods that are anti-inflammatory seem to lower the risk of breast cancer; perhaps, preventive measure for cancer may be at the grocery store rather than the pharmacy.   The body’s immune system flings into action when
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Moles on the skin are a known risk factor for melanoma. A recent study of young teenagers examined risk factors associated with having mole-prone skin in late adolescence.   Melanoma, a type of skin cancer, causes mortality and continues to become more prevalent. Having pigmented moles in adulthood is a strong risk factor for melanoma.
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Researchers investigated the safety and efficacy of combined fulvestrant and buparlisib therapy for the treatment of advanced hormone receptor-positive, HER2-negative breast cancer, and explored PI3K activity as an indicator of treatment response. The study found that combined fulvestrant and buparlisib therapy improves progression-free survival.   Though hormone receptor (HR)-positive tumours are the most common type
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Cancer patients require psychosocial assistance in addition to medical treatments, which respectively involves the general practitioner and the oncologist. A recent study sheds light on oncologists’ opinion about the involvement of general practitioners in treating cancer patients, which paves the way to future improvements in establishing communication bridges between general practitioners and oncologists for the
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