Aging

A recent meta-analysis investigates whether sex, age, and a particular genotype are associated with a greater risk of developing Alzheimer’s disease. Alzheimer’s Disease (AD) is a chronic neurodegenerative condition, characterized by cognitive deficits in memory, thinking, and behaviour. Research has shown that different environmental, genetic, and socioeconomic cues can increase the risk of developing Alzheimer’s
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The relationship between memory and time has been studied extensively but is still poorly understood. A new study assessed memory and time deficits in Alzheimer’s disease (AD) patients in their home environments. It is widely accepted that as time passes, the ability to recall events and specific information declines. Episodic memory is the type of
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A recent analysis of geriatric patients hospitalized through emergency departments shows that proper geriatric assessments of older patients may reduce admission rates. A recent article published in Age and Ageing by the Oxford University Press reviewed the evidence behind performing comprehensive geriatric assessments (CGA) for more elderly patients that present at the emergency department. The
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In a recent study, researchers sought to identify proteins important for the anti-neural plasticity effects of histone deacetylase 2 (Hdac2) in Alzheimer’s disease. How Cells Control Gene Activity  Acetylation is one method by which cells control gene activity by the addition or removal of acetyl groups. Acetylation is performed by enzymes called acetyltransferases on histone
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Medication administration and management is a real problem in patients suffering from medical conditions associated with cognitive deficits. A recent study examined the experience of family members as they help take care of elder family members with Alzheimer’s disease. Compliance is an ongoing issue in medicine, particularly for elderly patients with medical conditions that cause
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A recently published study in Science determines whether it is possible for chimpanzees to develop Alzheimer ’s disease as they age. Alzheimer’s disease is a type of dementia that causes problems with cognition, behaviour, and memory. Alzheimer’s is a progressive, debilitating disease with no cure. The full diagnosis occurs when dementia is accompanied by two distortions
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In a 2017 study, researchers examined the relationship between rare gene variants and early-onset Alzheimer’s disease risk. Variants in a number of genes were identified, including PSD2, TCIRG1, and RIN3 – genes important to endolysosomal function. Mutations in a number of key genes have been implicated in the development of 5-10% of early-onset Alzheimer’s disease
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Tau proteins might be associated with dementia (including Alzheimer’s disease) as well as mild cognitive impairment and cognitive decline. The current study found that higher levels of total tau in blood plasma were significantly associated with cognitive decline. Dementia represents a broad category of neurological diseases that cause gradual cognitive decline over time. The most
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  Recently, the end of life care experienced by older adult individuals has sparked interest and observations have been made to identify the potential risk factors for aggressive care along with an evaluation of the cost. This highlights the need to keep families informed about what to expect when an older adult in their midst
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  Research examines the prevalence of abuse in older adults globally and in turn highlight the risk and need for increased protection services in this regard.   Elderly abuse continues to be a growing problem. In 2015 there were an estimated 901 million older adults, or adults over the age of 65, globally.  Psychological abuse
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  A recent article, published in The American Journal of Clinical Nutrition, investigates how the metabolism of eicosapentaenoic acid (EPA) and arachidonic acid (AA) changes with age.   There are significant metabolic and biological changes that occur with progressing age. These changes must be taken into consideration to maintain a healthy and balanced nutritional intake.
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Reducing maternal mortality rates has been a long-term goal of public health officials. In the past, the majority of research has focused on infant mortality and its relation to the mother’s age (maternal age), leaving the connection between maternal mortality rates and maternal age understudied. Recent research indicates that maternal mortality rates increase significantly after
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Recent studies have identified an association between the height of an individual and their risk of various age-related diseases. Researchers investigated the relationship between adult height and healthy aging in a study population of female nurses and found that height has effects on healthy aging; they also found this association could be modified through dietary
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Obesity is common among older adults and has been found to exacerbate age-related functional decline and contribute to frailty. Researchers found that the most effective strategy to elicit weight loss while maintaining physical function and preserving lean muscle mass and bone mineral density is a combination of aerobic exercise and resistance training in addition to
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A cohort study in Japan investigated the relationship between eating citrus fruits and developing dementia later in life. The authors controlled for a number of confounding factors, and found that the consumption of citrus is linked with lower incidence of dementia.   Neurodegeneration leading to loss of cognitive function, generally referred to as dementia, is
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Exercise is linked to a longer, healthier life but the mechanisms are unclear. To determine how exercise and health are linked, Tucker shows in Preventive Medicine that physical activity is associated with longer telomeres, which are linked to reduced cellular aging.   Exercise reduces the risk of many chronic diseases, including diabetes and hypertension, and
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Diagnosis of mild-cognitive impairment (MCI) and, in many cases, the subsequent incident dementia in the elderly has proven to be difficult with current methods such as cerebrospinal fluid biomarker analysis. An article in JAMA Neurology discusses how a dual-task gait performance paradigm was used successfully as a diagnostic marker of progression to dementia in elderly
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Researchers out of France and Monaco recently finished one of the longest and largest studies on Alzheimer’s disease. The study focused on using multidomain lifestyle intervention with Omega 3 supplementation for Alzheimer’s patients. The results, unfortunately, were insignificant, but do provide swaths of new data and show potential for new treatment approaches that are less
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As demographics change in developed countries, a plethora of research is being done to better understand aging. The majority of research looks at how we can slow or (at least) improve the mental and physiological conditions of this inevitable process. Virtual reality is an exciting opportunity for older adults to escape their physical and mental
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